#35 - 🎯 No more carb counting?

Hey readers! 👋

Welcome to another week of T1D news! This week's lineup is packed with updates on automated insulin delivery systems, some fascinating research on diet and gut health, and a notable step forward in fully closed-loop technology. Plus, we've got a deep dive into the 2026 ADA Standards of Care that's worth your attention. Let's jump in!

CamDiab earns nod for fully closed-loop insulin delivery algorithm marks a significant milestone as the first commercially available system eliminating carb counting and pre-meal bolusing entirely. The myLife CamAPS FX app works with TecMed pumps and major CGMs including FreeStyle Libre 3 and Dexcom G6. – Drug Delivery Business

Automated basal insulin delivery versus multiple daily injections in type 1 diabetes presents solid evidence from a multicenter trial showing AID systems reduced HbA1c by 0.7% in those starting above 8.0%, while also cutting time below 70 mg/dL by 4.8% in well-controlled patients. Safety profiles remained excellent across both pediatric and adult populations. – Medtronic Diabetes

Medtronic touts time in range outcomes with MiniMed 780G reveals that users following optimal settings achieved 76.3% time in range even on days when meal boluses were missed. The key? SmartGuard with a 100 mg/dL target and two-hour active insulin time. – Drug Delivery Business

What is twiist introduces Sequel Med Tech's new AID system featuring the widest customizable glucose target range (87-180 mg/dL) and updates basal insulin every five minutes based on a six-hour forecast. The compact pump weighs under 2 oz yet holds 300 units, and its iiSure technology detects blockages up to nine times faster than competitors. – Tidepool

Sensura to showcase non-invasive glucose monitoring tech at CES previews a prototype platform featuring both handheld and wearable devices designed to eliminate fingersticks entirely using optical sensing and AI analytics. – Drug Delivery Business

Eversense 365 CGM System offers a full-year implantable sensor requiring just one fingerstick calibration weekly after day 13, with a 91% low-glucose detection rate. – Eversense

Gut microbiome profiles linked to Mediterranean diet adherence found that higher Mediterranean diet adherence correlated with lower HbA1c (7.1% vs 7.7%) and better time in range among 253 adults with T1D. Those following the diet showed increased Faecalibacterium prausnitzii, a beneficial gut bacteria. – Elsevier B.V.

Nutrition and healthy lifestyles for children with early-stage T1D suggests that low-glycemic-index diets may help delay progression to stage 3 T1D, while balanced eating and moderate activity support overall health. – S. Karger AG

Oral Akkermansia muciniphila may ameliorate immune dysregulation showed this probiotic improved intestinal barrier function and increased regulatory T cells in a mouse model, though metabolic parameters remained unchanged. – Baishideng Publishing Group Inc

Depression and anxiety prevalence in Saudi adults with T1D found over half (54.9%) screened positive for depression and 45.1% for anxiety. Better self-care adherence was inversely correlated with both conditions. – PubMed

Arabic T1-DDS validation study revealed 72.4% of participants reported moderate-to-high diabetes distress, with insulin pump use appearing protective. – PubMed

Family and self-resilience mediate distress and self-management in adolescents, suggesting interventions targeting resilience at both levels could improve outcomes. – PubMed

#1728 ADA Standards of Care for 2026 breaks down the new guidelines, including hospital safety protocols preventing basal insulin from being withheld and the first formal endorsement of GLP-1 agonists for obesity in T1D. The hosts note that while these updates are welcome, many practices have been adopted by the community years before appearing in official standards. – Scott Benner, Juicebox Podcast

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